Nothing in your cart

Uh oh! Your cart is empty 😢

One of these products might be what you're after...

No recent items

Can A Glass (or two) of Red Wine Help Prolong Your Life?

Glass of Red Wine with bottle and peanuts

What Are The Benefits of Resveratrol?

Studies have suggested that resveratrol may offer numerous health benefits, due to its powerful antioxidant properties and positive effects on various aspects of well-being.

If you’ve ever heard of red wine being good for you and helping lower cholesterol – chances are, it’s because people are talking about the benefits of resveratrol, which is found in the skins and seeds of grapes. As well as naturally occurring in red wine and other foods like peanuts, resveratrol has been linked to several health benefits including protecting brain function and lowering blood pressure.

To date, most of the research on resveratrol’s benefits has been done on animals and in test tubes, but studies are being undertaken on humans about supplementing resveratrol and its benefits.

Can I Lower Blood Pressure with Resveratrol?

Due to its properties that make it a powerful antioxidant, resveratrol can help lower blood pressure when used as a supplement.

A 2015 review concluded that high doses of resveratrol may help reduce the pressure on artery walls when the heart beats. Known as systolic blood pressure, the upper number in blood pressure readings, this may help with lowering. Systolic blood pressure tends to go up in age as arteries stiffen, and high numbers are a risk factor for heart disease. Therefore, it’s fair to suggest that resveratrol can help reduce these risks.

Research has also suggested that resveratrol can help produce more nitric oxide, which causes blood vessels to relax, therefore lowering blood pressure.

Resveratrol for Healthy Blood Fats

A 2016 study (on mice) saw subjects fed a diet high in protein and polyunsaturated fats, as well as resveratrol supplements. The results of the study saw the average total cholesterol levels and body weight of the mice decrease, but their levels of cholesterol HDL (known as good cholesterol) increased. The researchers suggested that resveratrol influenced cholesterol levels by reducing the effect of an enzyme that controls its production.

Due to its antioxidant powers, it’s suggested that resveratrol can decrease the oxidisation of LDL cholesterol (known as bad cholesterol). Oxidation of bad cholesterol contributes to the build-up of things like plaque on artery walls.

One study gave participants grape extract boosted with extra resveratrol. After six months, their levels of bad cholesterol and oxidised LDL had reduced, compared with those who took a placebo or extract without the added resveratrol.

Can Resveratrol Slow Down Aging?

Resveratrol’s ability to extend the lifespan of different organisms is an increasing area of research. Some research results are suggesting that resveratrol activates genes that ward off diseases linked to aging.

But this early research is being done in organisms and hasn’t progressed to the stage of testing in humans so it’s not clear yet if it would have similar effects for humans. A review of several studies into the role of resveratrol in extending lifespans found it helped in 60 percent of the organisms studied, but its effects were strongest in organisms that weren’t related to humans, like worms and fish.

Can Resveratrol Protect the Brain from Age Related Decline?

Potentially! Several studies have suggested that drinking red wine, partly due to the antioxidant and anti-inflammatory aspects of resveratrol, can help slow down age-related cognitive decline and diseases like Alzheimer’s. That’s a win for the wine lovers out there – but maybe don’t go relying on that alone to help you in your old age, a red wine diet has other potentially negative health impacts!

Some studies have shown that resveratrol can interfere with protein fragments called beta-amyloids, which are crucial to forming the plaques that are a hallmark of Alzheimer’s disease. The compound may set off a chain of events that protect brain cells from damage.

Scientists however are still studying how well the human body can make use of resveratrol in supplement form and how that can protect the brain. 

All in all, it’s looking promising for the effects of resveratrol on the brain.

Resveratrol to Treat Diabetes

From studies in animals, resveratrol is looking promising for helping treat diabetes, including increasing insulin sensitivity and preventing diabetes related complications.

It’s been suggested that resveratrol may stop enzymes from turning glucose into sorbitol, a sugar alcohol, of which a build-up can create oxidative stress that causes cell damage.

It’s also suggested that resveratrol may have benefits around preventing oxidative stress, activating a protein that helps the body metabolise gluten, and helping decrease inflammation, a key contributor to chronic diseases.

Resveratrol for Healthy Joints

Research is also showing positive benefits of resveratrol for joint pain and mobility. Some studies have suggested that when taken as a supplement, resveratrol may help cartilage from deteriorating. That cartilage breakdown is what can cause joint pain, a major symptom of arthritis.

One study on rabbits used resveratrol in the knee joints of those with arthritis and found the rabbits who had resveratrol suffered less damage than those who didn’t. Other research on animals and in test tubes has suggested that resveratrol can help reduce inflammation and prevent damage to joints.

How Much Resveratrol Should I Take?

Resveratrol is a product that should be discussed with a medical professional before adding as a supplementary product in your diet. No major risks have been discovered to adding resveratrol to your diet, however there are some concerns around how it can impact with other medications.

Bulk Nutrients Expert - Ebony Abblitt

Ebony Abblitt

Ebony is our resident wordsmith here at Bulk! A reforming journalist and a graduate of the University of Tasmania, she's our resident copywriter, cat mum, pilates princess and (self appointed) Chief Swiftie!

More about Ebony Abblitt

References:

  1. Bonnefont-Rousselot, D. (2016). Resveratrol and Cardiovascular Diseases. Nutrients, 8(5), p.250. doi: https://doi.org/10.3390/nu8050250.
  2. ‌Liu, Y., Ma, W., Zhang, P., He, S. and Huang, D. (2015). Effect of resveratrol on blood pressure: A meta-analysis of randomized controlled trials. Clinical Nutrition, 34(1), pp.27–34. doi: https://doi.org/10.1016/j.clnu.2014.03.009.
  3. ‌Xia, N., Förstermann, U. and Li, H. (2014). Resveratrol and Endothelial Nitric Oxide. Molecules, 19(10), pp.16102–16121. doi: https://doi.org/10.3390/molecules191016102.
  4. Mendes, K.L., de Pinho, L., Andrade, J.M.O., Paraíso, A.F., Lula, J.F., Macedo, S.M., Feltenberger, J.D., Guimarães, A.L.S., de Paula, A.M.B. and Santos, S.H.S. (2016). Distinct metabolic effects of resveratrol on lipogenesis markers in mice adipose tissue treated with high-polyunsaturated fat and high-protein diets. Life Sciences, [online] 153, pp.66–73. doi: https://doi.org/10.1016/j.lfs.2016.04.014.
  5. ‌Witztum, J.L. and Steinberg, D. (1991). Role of oxidized low density lipoprotein in atherogenesis. Journal of Clinical Investigation, 88(6), pp.1785–1792. doi: https://doi.org/10.1172/jci115499.
  6. Tomé-Carneiro, J., Gonzálvez, M., Larrosa, M., García-Almagro, F.J., Avilés-Plaza, F., Parra, S., Yáñez-Gascón, M.J., Ruiz-Ros, J.A., García-Conesa, M.T., Tomás-Barberán, F.A. and Espín, J.C. (2012). Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: A triple-blind, 6-month follow-up, placebo-controlled, randomized trial. Molecular Nutrition & Food Research, 56(5), pp.810–821. doi: https://doi.org/10.1002/mnfr.201100673.
  7. ‌Howitz, K.T., Bitterman, K.J., Cohen, H.Y., Lamming, D.W., Lavu, S., Wood, J.G., Zipkin, R.E., Chung, P., Kisielewski, A., Zhang, L.-L., Scherer, B. and Sinclair, D.A. (2003). Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature, [online] 425(6954), pp.191–196. doi: https://doi.org/10.1038/nature01960.
  8. ‌Hubbard, B.P., Ana, Dai, H., Li, J., Case, A., Considine, T., Riera, T.V., Lee, J.Y., Sook Yen E, Lamming, D.W., Pentelute, B.L., Schuman, E., Stevens, L.A., Alvin, Armour, S.M., Shaday Michan, Zhao, H., Jiang, Y., Sweitzer, S. and Blum, C.A. (2013). Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators. 339(6124), pp.1216–1219. doi: https://doi.org/10.1126/science.1231097.
  9. ‌Pallauf, K., Rimbach, G., Rupp, P.M., Chin, D. and Wolf, I.M.A. (2016). Resveratrol and Lifespan in Model Organisms. Current Medicinal Chemistry, [online] 23(41), pp.4639–4680. doi: https://doi.org/10.2174/0929867323666161024151233.
  10. ‌Granzotto, A. and Zatta, P. (2014). Resveratrol and Alzheimerâ€TMs disease: message in a bottle on red wine and cognition. Frontiers in Aging Neuroscience, 6. doi: https://doi.org/10.3389/fnagi.2014.00095.
  11. ‌Panza, F., Frisardi, V., Seripa, D., Logroscino, G., Santamato, A., Imbimbo, B.P., Scafato, E., Pilotto, A. and Solfrizzi, V. (2012). Alcohol consumption in mild cognitive impairment and dementia: harmful or neuroprotective? International Journal of Geriatric Psychiatry, 27(12), pp.1218–1238. doi: https://doi.org/10.1002/gps.3772.
  12. Regitz, C., Fitzenberger, E., Mahn, F.L., Dußling, L.M. and Wenzel, U. (2015). Resveratrol reduces amyloid-beta (Aβ1–42)-induced paralysis through targeting proteostasis in an Alzheimer model of Caenorhabditis elegans. European Journal of Nutrition, 55(2), pp.741–747. doi: https://doi.org/10.1007/s00394-015-0894-1.
  13. ‌Granzotto, A. and Zatta, P. (2014). Resveratrol and Alzheimerâ€TMs disease: message in a bottle on red wine and cognition. Frontiers in Aging Neuroscience, 6. doi: https://doi.org/10.3389/fnagi.2014.00095.
  14. ‌Moussa, C., Hebron, M., Huang, X., Ahn, J., Rissman, R.A., Aisen, P.S. and Turner, R.S. (2017). Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease. Journal of Neuroinflammation, 14(1). doi: https://doi.org/10.1186/s12974-016-0779-0.
  15. ‌Vallianou, N.G., Evangelopoulos, A. and Kazazis, C. (2013). Resveratrol and Diabetes. The Review of Diabetic Studies, [online] 10(4), pp.236–242. doi: https://doi.org/10.1900/rds.2013.10.236.
  16. ‌Frojdo, S., Durand, C. and Pirola, L. (2008). Metabolic Effects of Resveratrol in Mammals - a Link Between Improved Insulin Action and Aging. Current Aging Sciencee, 1(3), pp.145–151. doi: https://doi.org/10.2174/1874609810801030145.
  17. ‌Soleas, G.J., Grass, L., Josephy, P.David., Goldberg, D.M. and Diamandis, E.P. (2002). A comparison of the anticarcinogenic properties of four red wine polyphenols. Clinical Biochemistry, [online] 35(2), pp.119–124. doi: https://doi.org/10.1016/s0009-9120(02)00275-8.
  18. ‌Chang, C.-C., Chang, C.-Y., Wu, Y.-T., Huang, J.-P., Yen, T.-H. and Hung, L.-M. (2011). Resveratrol retards progression of diabetic nephropathy through modulations of oxidative stress, proinflammatory cytokines, and AMP-activated protein kinase. Journal of Biomedical Science, [online] 18(1), p.47. doi: https://doi.org/10.1186/1423-0127-18-47.
  19. ‌Mobasheri, A., Henrotin, Y., Biesalski, H.-K. and Shakibaei, M. (2012). Scientific Evidence and Rationale for the Development of Curcumin and Resveratrol as Nutraceutricals for Joint Health. International Journal of Molecular Sciences, 13(4), pp.4202–4232. doi: https://doi.org/10.3390/ijms13044202.
  20. ‌Elmali, N., Baysal, O., Harma, A., Esenkaya, I. and Mizrak, B. (2007). Effects of resveratrol in inflammatory arthritis. Inflammation, [online] 30(1-2), pp.1–6. doi: https://doi.org/10.1007/s10753-006-9012-0.
  21. ‌Csaki, C., Mobasheri, A. and Shakibaei, M. (2009). Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis. Arthritis Research & Therapy, [online] 11(6), p.R165. doi: https://doi.org/10.1186/ar2850.

Popular Posts from the Bulk Blog

With over 700 recipes and articles, the Bulk Nutrients Blog has something for everyone! Find a new workout, meet our ambassadors or take a deep dive into our products today.

Compare all Bulk Nutrients proteins

Popular Proteins

Popular Products

Popular Categories

About Bulk Nutrients

We're an Australian manufacturer and supplier of high quality sports supplements.

Operating since 2008, Bulk Nutrients has become one of the premier Australian brands to supply nutritional products to top level athletes, competitors and those on a journey to a healthier lifestyle.

Find out more about Bulk.

Contact Bulk Nutrients

One thing that sets Bulk Nutrients apart is that we love to talk to our customers!

Whether you need product advice, help with the website or need a change made to your order... call us on +61 3 6266 4725.

If you prefer email you can email us day or night at info@bulknutrients.com.au

For online chat, hit the 'Chat' button in the bottom right hand corner of your screen and you'll be connected to one of our lovely customer service team.

Or if you'd like to get in touch through our online contact form, that's cool too!

Follow us on Social Media

Bulk Nutrients on FacebookCheck out Bulk Nutrients' Instagram postsView Bulk Nutrients' TikTok contentView Bulk Nutrients' YouTube Channel

Resources

Information

We acknowledge the Traditional Owners of the land on which our organisation operates, the Melukerdee People of the South East Nation and pay our respects to Elders past, present, and emerging.

Bulk Nutrients is proudly
Australian owned and operated.

7 Crabtree Road, Grove, Tasmania, 7109.
ABN: 17 158 981 447

Terms & ConditionsSustainability StrategyPrivacy PolicyPayment InformationSitemap

All prices are in Australian dollars (AUD) and include GST unless otherwise stated.
All content copyright © Bulk Nutrients 2008 - 2024